Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Copa Airlines

The cheapest airline(s) flying from Santo Domingo to Medellin is Copa Airlines.

  • Copa Airlines Copa Airlines
  • Arajet Arajet
  • Avianca Avianca
  • JetBlue Airways JetBlue Airways
  • American Airlines American Airlines
  • United Airlines United Airlines
Cheapest Month February

Travel Period: February 2025 - January 2026

The cheapest month(s) to fly from Santo Domingo to Medellin is February.

  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
  • Jan 2026
Cheapest Day of the Week Thursday

The cheapest day(s) of the week to fly from Santo Domingo to Medellin is Thursday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Thu, 2 Jan, 2025

  • Time Earliest
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  • Depart Earliest
    • Earliest
    • Latest
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    • Earliest
    • Latest
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  • Airline Filter by Airline
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  • Availability
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  • 21:28 SDQ
    22:57 MDE
    2Hrs, 29m Direct
  • SDQSanto Domingo Las Americas Airport 21:28 - MDE 22:57 2h 29m Direct
  • SDQSanto Domingo Las Americas Airport 21:28
  • MDEMedellin Jose Maria Cordova Intl Airport 22:57
  • 2h 29m
  • Direct
  • Wingo (P5 7423)Boeing 737 800
  • Wingo (P5 7423)
    • -
    • -
    • W
    • -
    • -
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  • Boeing 737 800
  • 07:00 SDQ
    10:05 MDE
    4Hrs, 05m Direct
  • SDQSanto Domingo Las Americas Airport 07:00 - MDE 10:05 4h 05m Direct
  • SDQSanto Domingo Las Americas Airport 07:00
  • MDEMedellin Jose Maria Cordova Intl Airport 10:05
  • 4h 05m
  • Direct
  • Arajet (DM 1740)Boeing 737 Max 8 Passenger
  • Arajet (DM 1740)
    • -
    • -
    • -
    • T
    • -
    • -
    • -
  • Boeing 737 Max 8 Passenger
  • 09:09 SDQ
    10:38 MDE
    2Hrs, 29m Direct
  • SDQSanto Domingo Las Americas Airport 09:09 - MDE 10:38 2h 29m Direct
  • SDQSanto Domingo Las Americas Airport 09:09
  • MDEMedellin Jose Maria Cordova Intl Airport 10:38
  • 2h 29m
  • Direct
  • Wingo (P5 7421)Boeing 737 800
  • Wingo (P5 7421)
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • Boeing 737 800
  • 10:13 SDQ
    11:45 MDE
    2Hrs, 32m Direct
  • SDQSanto Domingo Las Americas Airport 10:13 - MDE 11:45 2h 32m Direct
  • SDQSanto Domingo Las Americas Airport 10:13
  • MDEMedellin Jose Maria Cordova Intl Airport 11:45
  • 2h 32m
  • Direct
  • Arajet (DM 1730)Boeing 737 Max 8 Passenger
  • Arajet (DM 1730)
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • Boeing 737 Max 8 Passenger
  • 13:30 SDQ
    16:35 MDE
    4Hrs, 05m Direct
  • SDQSanto Domingo Las Americas Airport 13:30 - MDE 16:35 4h 05m Direct
  • SDQSanto Domingo Las Americas Airport 13:30
  • MDEMedellin Jose Maria Cordova Intl Airport 16:35
  • 4h 05m
  • Direct
  • Arajet (DM 1740)Boeing 737 Max 8 Passenger
  • Arajet (DM 1740)
    • M
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  • Boeing 737 Max 8 Passenger
  • 14:50 SDQ
    16:22 MDE
    2Hrs, 32m Direct
  • SDQSanto Domingo Las Americas Airport 14:50 - MDE 16:22 2h 32m Direct
  • SDQSanto Domingo Las Americas Airport 14:50
  • MDEMedellin Jose Maria Cordova Intl Airport 16:22
  • 2h 32m
  • Direct
  • Arajet (DM 1738)Boeing 737 Max 8 Passenger
  • Arajet (DM 1738)
    • -
    • -
    • -
    • -
    • F
    • -
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  • Boeing 737 Max 8 Passenger
  • 18:08 SDQ
    19:40 MDE
    2Hrs, 32m Direct
  • SDQSanto Domingo Las Americas Airport 18:08 - MDE 19:40 2h 32m Direct
  • SDQSanto Domingo Las Americas Airport 18:08
  • MDEMedellin Jose Maria Cordova Intl Airport 19:40
  • 2h 32m
  • Direct
  • Arajet (DM 1738)Boeing 737 Max 8 Passenger
  • Arajet (DM 1738)
    • -
    • T
    • -
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    • S
  • Boeing 737 Max 8 Passenger
  • 18:08 SDQ
    19:40 MDE
    2Hrs, 32m Direct
  • SDQSanto Domingo Las Americas Airport 18:08 - MDE 19:40 2h 32m Direct
  • SDQSanto Domingo Las Americas Airport 18:08
  • MDEMedellin Jose Maria Cordova Intl Airport 19:40
  • 2h 32m
  • Direct
  • Arajet (DM 1736)Boeing 737 Max 8 Passenger
  • Arajet (DM 1736)
    • -
    • -
    • -
    • -
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    • -
  • Boeing 737 Max 8 Passenger
  • 09:15 SDQ
    15:00 MDE
    6Hrs, 45m 1 Stop (SJU)
  • SDQSanto Domingo Las Americas Airport 09:15 - MDE 15:00 6h 45m 1 Stop (SJU) San Juan
  • SDQSanto Domingo Las Americas Airport 09:15
    SJUSan Juan Luis Munoz Marin Intl Airport 13:08
  • SJUSan Juan Luis Munoz Marin Intl Airport 10:19
    MDEMedellin Jose Maria Cordova Intl Airport 15:00
  • 6h 45m (2h 49m)
  • 1 Stop SJU · San Juan 2h 49m
  • JetBlue Airways (B6 2538)Airbus
    JetBlue Airways (B6 1703)Airbus
  • JetBlue Airways (B6 2538)
    • -
    • T
    • -
    • T
    • F
    • -
    • S
  • 10:02 SDQ
    15:58 MDE
    6Hrs, 56m 1 Stop (BOG)
  • SDQSanto Domingo Las Americas Airport 10:02 - MDE 15:58 6h 56m 1 Stop (BOG) Bogota
  • SDQSanto Domingo Las Americas Airport 10:02
    BOGBogota Airport 14:56
  • BOGBogota Airport 11:42
    MDEMedellin Jose Maria Cordova Intl Airport 15:58
  • 6h 56m (3h 14m)
  • 1 Stop BOG · Bogota 3h 14m
  • Wingo (P5 7083)Boeing 737 800
    Wingo (P5 7272)Boeing 737 800
  • Wingo (P5 7083)
    • -
    • -
    • -
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    • -
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    • S
  • 11:50 SDQ
    18:11 MDE
    7Hrs, 21m 1 Stop (BOG)
  • SDQSanto Domingo Las Americas Airport 11:50 - MDE 18:11 7h 21m 1 Stop (BOG) Bogota
  • SDQSanto Domingo Las Americas Airport 11:50
    BOGBogota Airport 17:10
  • BOGBogota Airport 13:25
    MDEMedellin Jose Maria Cordova Intl Airport 18:11
  • 7h 21m (3h 45m)
  • 1 Stop BOG · Bogota 3h 45m
  • Avianca (AV 209)Airbus A320 Neo
    Avianca (AV 9304)Airbus
  • Avianca (AV 209)
    • M
    • T
    • -
    • -
    • -
    • -
    • -
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What’s the fastest flight time from Santo Domingo to Medellin?

The fastest flight time for direct flights from Santo Domingo to Medellin is 2 hours 29 minutes. Check latest flight schedules & prices on Wego.

How far is Medellin from Santo Domingo?

The flight distance between Santo Domingo and Medellin is 1493km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 07:00. The last flight of the day departs at 21:28. See the full list of flight times on Wego.

How many airlines offer direct flights from Santo Domingo to Medellin?

There are 2 airlines that offer direct flights from Santo Domingo to Medellin. Find out the list of airlines on Wego.